Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) originally marketed as Brufen. Molecular formula : C13H18O2
MW : 206.27
CAS No. :15687-27-1
Properties : the white crystalline powder. 75-77 ° C melting point. Do not dissolve in water, soluble in alcohol, chloroform, ethyl ether, acetone. Eliminate the Stink from there, flavorless.
Production methods : isobutyl acetophenone by condensation, hydrolysis, eliminate, oxidation, and were derived.
Application : to have anti-inflammatory, analgesic and antipyretic effects. The treatment of rheumatoid arthritis and rheumatoid up to the efficacy of aspirin and Phenylbutazone. The application in the treatment of rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and other neuritis. The goods in the United States in 1985 drug sales sequencing ranks 13rd
Certificate Of Analysis: USP28 Edition
|
Item |
Standard |
Test Result |
|
Identification |
Accord with USP28 |
Passes |
|
Assay（HPLC） |
97.0%～103.0% |
98.39% |
|
Water |
≤1.0% |
0.03% |
|
Heavy metals |
≤0.002% |
＜0.001% |
|
Residue on ignition |
≤0.5% |
0.05% |
|
Organic volatile impurities |
Accord with USP28 |
Passes |
|
4-isobutylacetophenone |
≤0.1% |
＜0.1% |
|
Chromatographic purity |
Accord with USP28 |
Passes |